Discriminate mechanisms that fit the same allele-frequency endpoint
A model can reproduce an observation while giving the wrong causal explanation. Population frequencies can change through selection, migration, mutation and drift, often together. An exact fit to one endpoint is therefore a starting point for discrimination, not a proof of mechanism.
Learning outcome: Fit both explanations at endpoint0.4, then change donor frequency while holding the endpoint fixed. Explain why the selection fit stays unchanged while the migration fit changes. Specify one independent observation and a predicted direction for each competing explanation.
Starting recap
Distinguish population mechanisms using explicit allele, genotype, life-cycle and sampling denominators; compare conditional explanations and independent falsifying evidence.
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Try
From p0.2 to0.4, selection w=(0.4×0.8)/(0.2×0.6)=8/3. With donor0.8, migration m=(0.4−0.2)/(0.8−0.2)=1/3. Substitution into both equations returns0.4 exactly; the fit alone chooses neither.
Open the experimentPredict
Can two models with different biological mechanisms both make an exact prediction of the same endpoint?
Experiment
Fit both explanations at endpoint0.4, then change donor frequency while holding the endpoint fixed. Explain why the selection fit stays unchanged while the migration fit changes. Specify one independent observation and a predicted direction for each competing explanation.
Compare distinct explanations of the same population change
Worked teaching model · synthetic values · Initial haploid p=0.2. Fit either selection-only relative contribution w=p′(1−p)/(p(1−p′)), or migration-only replacement m=(p′−p)/(pDonor−p). Both match one endpoint exactly; neither is thereby established.
Reset keeps your prediction, captures and practice history.
An exactly fitted endpoint can be compatible with more than one biological mechanism.
Independent survival/reproduction records, migrant assignment and repeated replicate/time observations can discriminate alternatives. The fitted values are conditional explanations, not measured parameters or proof that drift and other mechanisms are absent.
| Quantity | Value | Unit |
|---|---|---|
| Observed initial A frequency | 0.2000000 | fraction |
| Observed final A frequency | 0.4000000 | fraction |
| Selection-only fitted relative contribution | 2.666667 | relative |
| Migration-only fitted replacement | 0.3333333 | fraction |
| Selection-only predicted endpoint | 0.4000000 | fraction |
| Migration-only predicted endpoint | 0.4000000 | fraction |
Retain prior predictions, settings and quantities in the notebook. These are original supplied/calculated comparisons, not physical specimen observations or laboratory participation.
An exactly fitted endpoint can be compatible with more than one biological mechanism.
Independent survival/reproduction records, migrant assignment and repeated replicate/time observations can discriminate alternatives. The fitted values are conditional explanations, not measured parameters or proof that drift and other mechanisms are absent.
Captures preserve recipes and replay their calculated results. They are synthetic model evidence, not physical measurements.
Understand
Apply
Public practice checks a specific claim. It does not establish independent mastery.
Initial p0.2 rises to0.5 with donor pD0.8. Find the selection-only w and migration-only m.
Continue
Completion requires a saved prediction, at least one capture and a reflection. Presence checks do not grade your reasoning.
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